Comparative Genomics: Using Fungi as Models (Topics in by Per Sunnerhagen, Jure Piskur

By Per Sunnerhagen, Jure Piskur

Fungal comparative genomics begun in 2000 by way of the genome sequencing of a number of yeast species. because then, over 30 fungal genome sequences became on hand. This set represents an enormous evolutionary divergence, but additionally includes heavily similar genomes. This quantity describes the right way to use this set of genomes to track occasions in genome evolution, to extract information regarding hugely conserved and not more conserved series parts, and to enhance novel tools in genomics.

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By Per Sunnerhagen, Jure Piskur

Fungal comparative genomics begun in 2000 by way of the genome sequencing of a number of yeast species. because then, over 30 fungal genome sequences became on hand. This set represents an enormous evolutionary divergence, but additionally includes heavily similar genomes. This quantity describes the right way to use this set of genomes to track occasions in genome evolution, to extract information regarding hugely conserved and not more conserved series parts, and to enhance novel tools in genomics.

Show description

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1998; O’Donnell et al. 2000), including the yeasts. Belloch et al. (2000) have demonstrated the utility of cytochrome oxidase II for resolution of Kluyveromyces species, Daniel et al. (2001) have successfully used actin-1 for species of Candida, and Kurtzman and Taxonomy and phylogenetic diversity among the yeasts 35 Table 3. Extent of nuclear DNA complementarity and nucleotide divergence in large subunit rDNA D1/D2 domains between certain closely related yeastsa % nDNA reassociation D1/D2 divergence 49 46 1 0 Pichia amylophila Pichia mississippiensis 27 4 Pichia toletana Pichia xylosa 29 1 Saccharomyces bayanus Saccharomyces pastorianus 72 0 Taxa Candida shehatae var.

1979). b Price et al. (1978). c Kurtzman (1984b). d Kurtzman (1990b). Characteristic (+ or - ) True Hyphae + Glucose fermentation + Lactose assimilation + Nitrate assimilation + Nitrate assimilation + - DNA relatedness (%) 78a 96b 97b 75c 100d high DNA relatedness that the pathogens Candida albicans, C. stellatoidea, and C. claussenii represent the same species. Following this work, Meyer and Phaff (1972) demonstrated high DNA homology between Candida lusitaniae and C. obtusa and between C. salmonicola and C.

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