By Yoshihito Yawata
This e-book offers the constitution and serve as of organic membranes to enhance the knowledge of cells in either basic and pathogenic states. lately, great quantities of recent details were gathered, specially approximately pathological stipulations, and there's now a lot proof correlating genotypes and phenotypes in common and sickness states. This booklet surveys the newest findings in study at the molecular biology, biochemistry, and genetics of the membranes of human crimson blood cells.
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Extra info for Cell Membrane. the Red Blood Cell as a Model
Some amphipathic compounds, which are permeable and can cross the membrane in their uncharged form, cause the membrane to extend toward the side of greater accumulation . It is a general rule that cationic compounds accumulate in the inner leaflet, which is negatively charged, and anionic compounds are distributed in the outer leaflet which is neutral. This variation is extremely sensitive, and can produce a change in the shape of the red cells. ) . Although this coupled bilayer hypothesis is very attractive, and can explain a number of phenomena well, a serious question has recently been raised by Nakao .
Liss, New York. Marchesi, V. , Gallo, R. C. ) (1982) Differentiation and Function of Hematopoietic Cell Surfaces. Liss, New York. Palek, J. ) (1983) Cytoskeletal Proteins. Semin. Hematol. 20: 139À242. 54 Schrier, S. L. ) (1985) The Red 55 56 57 58 59 60 61 62 63 Blood Cell Membrane, in: Clinics Haematol. 14: 1À280. , Cohen, C. , Lux, S. , Palek, J. ) (1986) Membrane Skeletons and Cytoskeletal Membrane Associations. Liss, New York. Lux, S. E. (1987) Disorders of the red cell membrane, in: Hematology of Infancy and Childhood (Nathan, D.
240: 26À28. Lux, S. E. (1979) Dissecting the red cell membrane skeleton. Nature 281: 426À429. Jacob, H. S. ) (1979) Blood Cell Membranes. I. Semin. Hematol. 16: 1À139. Lux, S. , Marchesi, V. , Fox, C. F. ) (1979) Normal and Abnormal Red Cell Memberanes. Liss, New York. Marchesi, V. , Gallo, R. C. ) (1982) Differentiation and Function of Hematopoietic Cell Surfaces. Liss, New York. Palek, J. ) (1983) Cytoskeletal Proteins. Semin. Hematol. 20: 139À242. 54 Schrier, S. L. ) (1985) The Red 55 56 57 58 59 60 61 62 63 Blood Cell Membrane, in: Clinics Haematol.