By Gerry Melino, David Vaux
This booklet on mobile demise includes 29 self-contained, peer-reviewed articles written via best scientists in every one box. It good points evaluate articles aimed toward undergraduates and non-specialists, which current simple info and supply access into the subsequent complex articles. those complex articles are written for postgraduate scholars and study employees, containing certain info and key references permitting the reader to enquire a selected region in additional intensity. The e-book is an important source for tutorial reasons in addition to a reference paintings for knowledgeable researchers within the box. The articles can be to be had electronically as a part of the acclaimed Encyclopedia of lifestyles Sciences (ELS).Key features:Provides a finished review at the learn of programmed cellphone death.Edited by way of leaders within the field.Clearly written and illustrated articles.Full color throughout.A spin-on to the acclaimed reference paintings, the Encyclopedia of lifestyles technology (ELS).Combines introductory details with insurance of the newest discoveries within the field.Features evaluation point articles for complicated scholars or humans new to a subject and extra complex articles for these requiring extra distinctive information.Serves as a reference paintings for complicated scholars in addition to researchers during this field.Ideal library buy for technological know-how, scientific, and know-how libraries in academia, executive, and undefined; clinical libraries; networks and consortia protecting those markets.
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Extra resources for Cell Death (Encyclopedia of Life Sciences)
Each cell initiates an incomplete process of asymmetric division, and a criss-cross exchange of transcription factors through the intercellular membrane that links the big mother cell and the small daughter cell will induce diﬀerentiation of the daughter cell into a spore, and death of the mother cell (Losick and Stragier, 1992). These successive processes of symmetry breaking and intercellular signalling – coupling survival of a part of the colony with death of another part – can be viewed either as examples of ‘murders’ by which some cells survive by killing their Cell Death & 2010, John Wiley & Sons, Ltd.
Elegans were derived from the exploration of genetic mutants with Ced-3 or Ced-4 loss-of-function, and with both Ced-3 or Ced-4 and Ced-9 loss-of-function. These studies implied that (i) there was only one molecular pathway of PCD in C. , 1991; Horvitz, 1999). This led to the concept of the existence of speciﬁc, death genes that emerged and became selected during evolution for their sole capacity to induce or repress self-destruction. In a somehow paradoxical manner, however, cell death seemed for a long time not to play any signiﬁcant role in C.
1994) Programmed cell death in Dictyostelium. Journal of Cell Science 107: 2691– 2704. Darwin C (1859) On the origin of species by means of natural selection. London: John Murray. uk/. Delivani P, Adrain C, Taylor RC, Duriez PJ and Martin SJ (2006) Role for CED-9 and Egl-1 as regulators of mitochondrial ﬁssion and fusion dynamics. Molecular Cell 21: 761–773. Derry WB, Putzke AP and Rothman JH (2001) Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance. Science 294: 591–595.